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TMCNet:  U.S. Patents Awarded to Inventors in Massachusetts (Feb. 26)

[February 26, 2013]

U.S. Patents Awarded to Inventors in Massachusetts (Feb. 26)

(Targeted News Service Via Acquire Media NewsEdge) Targeted News Service Targeted News Service ALEXANDRIA, Va., Feb. 26 -- The following federal patents were awarded to inventors in Massachusetts.

*** Millennium Pharmaceuticals Assigned Patent ALEXANDRIA, Va., Feb. 26 -- Millennium Pharmaceuticals, Cambridge, Mass., has been assigned a patent (8,378,099) developed by six co-inventors for "boronic ester and acid compounds, synthesis and uses." The co-inventors are Julian Adams, Boston, Yu-Ting Ma, Needham, Mass., Ross L. Stein, Sudbury, Mass., Matthew Baevsky, Grafton, Mass., Louis Grenier, Medford, Mass., and Louis Plamondon, Belmont, Mass.



The abstract of the patent published by the U.S. Patent and Trademark Office states: "Disclosed herein is a method for reducing the rate of degradation of proteins in an animal, comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses." The patent application was filed on Aug. 19, 2011 (13/213,157). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,78,099.PN.&OS=PN/83,78,099&RS=PN/83,78,099 Written by Amal Ahmed; edited by Jaya Anand.

*** Declion Pharmaceuticals Assigned Patent ALEXANDRIA, Va., Feb. 26 -- Declion Pharmaceuticals, Boxford, Mass., has been assigned a patent (8,378,072) developed by Dustan Bonnin, Belmont, Mass., for "methods for designing and synthesizing directed sequence polymer compositions via the directed expansion of epitope permeability." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The instant invention comprises a process for the solid phase synthesis of directed epitope peptide mixtures useful in the modulation of unwanted immune responses, such process defined by a set of rules regarding the identity and the frequency of occurrence of amino acids that substitute a base or native amino acid of a known epitope. The resulting composition is a mixture of related peptides for therapeutic use." The patent application was filed on April 13, 2007 (11/787,229). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,78,072.PN.&OS=PN/83,78,072&RS=PN/83,78,072 Written by Amal Ahmed; edited by Jaya Anand.

*** Massachusetts Inventor Develops Patent for Adjustable Bed Frame ALEXANDRIA, Va., Feb. 26 -- Martin B. Rawls-Meehan, Lexington, Mass., has developed a patent (8,375,488) for an adjustable bed frame.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "An adjustable bed frame assembly includes a center frame comprising two substantially parallel side frame members connected by two substantially parallel connector frame members. The adjustable bed frame assembly also includes a base frame that includes a plurality of legs for mounting on a floor is rigidly affixed to the center frame. The adjustable bed frame assembly further includes a head frame that comprises two substantially parallel side frame members connected by at least one connector frame member. The adjustable bed frame assembly also includes an actuator for raising and lowering the head frame." The patent application was filed on Sept. 15, 2011 (13/233,373). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,75,488.PN.&OS=PN/83,75,488&RS=PN/83,75,488 Written by Amal Ahmed; edited by Jaya Anand.

*** Massachusetts Inventor Develops Patent for Novelty Associated with Beverages ALEXANDRIA, Va., Feb. 26 -- Andrew P. Golden, Jamaica Plains, Mass., has developed a patent (8,376,161) for a "novelty associated with beverages." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Systems, methods, and means for providing a novelty item are provided. In some embodiments, a stopper comprises a body, having an inner chamber and a top portion, a novelty item disposed within the inner chamber, and a disk placed on an outer surface of the body removably holding the novelty item within the inner chamber." The patent application was filed on Aug. 9, 2010 (12/852,924). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,76,161.PN.&OS=PN/83,76,161&RS=PN/83,76,161 Written by Amal Ahmed; edited by Jaya Anand.

*** Genzyme Assigned Patent ALEXANDRIA, Va., Feb. 26 -- Genzyme, Cambridge, Mass., has been assigned a patent (8,378,036) developed by Gary S. Rea, Northboro, Mass., for a "method of drying a material having a cohesive phase." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A method for drying a material such as a polymer hydrogel which passes through a cohesive phase as it dries is disclosed. The method comprises agitating a composition while removing liquid until the solids content of the composition reaches a level at which the composition enters a cohesive phase, halting agitation, removing liquid from the composition in the absence of agitation, and resuming agitation. Practice of the present invention can eliminate the problems associated with adhesion of a material to itself and to process equipment during the cohesive phase." The patent application was filed on Feb. 27, 2012 (13/406,193). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,78,036.PN.&OS=PN/83,78,036&RS=PN/83,78,036 Written by Amal Ahmed; edited by Jaya Anand.

*** University of Illinois Assigned Patent ALEXANDRIA, Va., Feb. 26 -- The University of Illinois, Urbana, Ill., has been assigned a patent (8,378,003) developed by six co-inventors for "highly permeable polymeric membranes." The co-inventors are Kumar Manish, Newton, Mass., Clark Mark, Chicago, Zilles L. Julie, Champaign, Ill., Mariusz Grzelakowski, Marina Del Rey, Calif., Rainer Nehring, Basel, Switzerland, and WolfGang Meier, Therwil, Switzerland.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Provided are substantially flat membranes that include a block or graft co-polymer and a water transport protein, such as Aquaporin-Z, or a synthetic mimic of such proteins. Also provided are methods of removing contaminants from a liquid, by contacting the liquid with a substantially flat membrane that includes a block or graft co-polymer and a water transport protein or synthetic mimic thereof. Also provided are methods of making such membranes. Further provided are compositions that include at least one active ingredient and vesicles surrounding the active ingredient, where the vesicles include a block or graft copolymer and a water transport protein or synthetic mimic surrounding the active ingredient. Also provided are methods that include administering such compositions to patients." The patent application was filed on Dec. 4, 2008 (12/745,692). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,78,003.PN.&OS=PN/83,78,003&RS=PN/83,78,003 Written by Amal Ahmed; edited by Jaya Anand.

*** Massachusetts Inventor Develops Patent for Handgun Storage Stack ALEXANDRIA, Va., Feb. 26 -- William S. Holmes Jr., Acton, Mass., has developed a patent (8,376,152) for a handgun storage stack.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "In one embodiment, the present invention provides a free-standing handgun stack for storing multiple handguns in a single column vertical stacking arrangement. In another embodiment the invention provides a handgun stack for storing multiple handguns in a single column vertical stacking arrangement wherein the handgun stack is retrofitable or inserted for permanent or removable attachment to the inside of a gun safe. In one aspect of this embodiment, the gun stack is configured to a height and width that takes up about the same amount of space as a long gun if such long gun were disposed or secured in a vertical position in the same space within the gun safe." The patent application was filed on May 3, 2012 (13/463,088). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,76,152.PN.&OS=PN/83,76,152&RS=PN/83,76,152 Written by Amal Ahmed; edited by Jaya Anand.

*** Boston University Assigned Patent ALEXANDRIA, Va., Feb. 26 -- Boston University, Boston, has been assigned a patent (8,378,064) developed by Mark W. Grinstaff, Brookline, Mass., and Michel Wathier, Brighton, Mass., for "hydrophilic polymers as medical lubricants and gels." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention provides new biopolymers which mimic the properties of natural polysaccharides found in vivo. The inventive polysaccharides can be used as viscosupplements, viscoelastics, tissue space fillers, and/or anti-adhesive agents. Also provided are pharmaceutical compositions comprising the inventive polymers and methods of using them including, for example, in the treatment of arthritic and sport-injured knee joints; in reconstruction or cosmetic procedures, intervertebral disc repair, treatment of vocal cord problems, treatment of urinary incontinence, and prevention of adhesion formation following abdominal or gynecological surgery." The patent application was filed on May 18, 2007 (12/301,410). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,78,064.PN.&OS=PN/83,78,064&RS=PN/83,78,064 Written by Amal Ahmed; edited by Jaya Anand.

*** Koninklijke Philips Electronics Assigned Patent ALEXANDRIA, Va., Feb. 26 -- Koninklijke Philips Electronics, Eindhoven, The Netherlands, has been assigned a patent (8,376,594) developed by John S. Park, Fall River, Mass., and Eugene R. Sartini, Fall River, Mass., for a "recessed lighting fixture with socket adjustment mechanism." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A recessed luminaire with adjustable socket assembly comprises a housing having a sidewall, a top wall and a lower opening allowing light output, a socket adjustment assembly disposed in the housing, the socket adjustment assembly having: a lamp socket connected to a socket carriage, a track having a socket carriage movably positioned on the track, wherein the carriage moves along the track and the lamp socket is movable in at least one of a vertical or a horizontal direction." The patent application was filed on Nov. 4, 2009 (12/612,407). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,376,594&OS=8,376,594&RS=8,376,594 Written by Arpi Sharma; edited by Anand Kumar.

*** Massachusetts Inventor Develops Patent for Method and Apparatus for Increasing Effectiveness of Abdominal Exercises ALEXANDRIA, Va., Feb. 26 -- Jeffrey T. Anderson, West Yarmouth, Mass., has developed a patent (8,376,920) for a "method and apparatus for increasing effectiveness of abdominal exercises." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Apparatus in the form of a wedge made of foam having a density capable of maintaining a user's spine extended during use is employed during abdominal exercise to prevent posterior pelvic tilt (PPT) during the exercise and thereby promote elastic remodeling of the spinal ligament." The patent application was filed on May 7, 2009 (12/437,017). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,376,920&OS=8,376,920&RS=8,376,920 Written by Arpi Sharma; edited by Anand Kumar.

*** Massachusetts Inventor Develops Patent for Real-time Traffic Condition Measurement Using GPS Data ALEXANDRIA, Va., Feb. 26 -- Edward H. Nortrup, Stoneham, Mass., has developed a patent (8,380,429) for a "real-time traffic condition measurement using GPS data." The abstract of the patent published by the U.S. Patent and Trademark Office states: "In embodiments of the present invention, a computer program may use GPS coordinates associated with cell phones located within multiple cars to measure real time traffic conditions. These traffic conditions may be measured based at least in part on using parameters including, but not limited to, a time of day, a day of the week, a weather condition, a road condition, or some other parameter relating to traffic conditions. The traffic conditions may be used to calculate a vehicle speed between two locations and predict related travel time. The real-time traffic condition information may be manually accessed by a user from their cell phone or automatically presented to a user's cell phone when the cell phone enters a specific geographic location or region." The patent application was filed on Nov. 14, 2011 (13/295,234). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,380,429&OS=8,380,429&RS=8,380,429 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Massachusetts Inventor Develops Patent for Golf Glove ALEXANDRIA, Va., Feb. 26 -- David P. Murphy, Quincy, Mass., has developed a patent (8,376,872) for a golf glove.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "A golf glove having a finger retaining component. The finger retaining component may be affixed to the glove of one hand at or near the index finger to receive and secure a finger or fingers from the other hand." The patent application was filed on Nov. 21, 2008 (12/275,482). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,376,872&OS=8,376,872&RS=8,376,872 Written by Arpi Sharma; edited by Anand Kumar.

*** Massachusetts Inventors Develop Patent for Mass Generation of Individual Virtual Servers, Virtual Web Sites, and Virtual Web Objects ALEXANDRIA, Va., Feb. 26 -- Henry Haugland, Natick, Mass., and Linda Wollschlager, Natick, Mass., have developed a patent (8,380,877) for a "mass generation of individual virtual servers, virtual web sites, and virtual web objects." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Techniques for inducing a contact to invoke a resource prepared by a promoter when the resource resides on a network include generating a resource location description for the resource. The resource location description includes a name of the contact. The promoter provides access to the resource at a location on the network according to the resource location description and also prepares a message to notify the contact about the resource location description. Thus a promoter can provide a web site for each contact whom the promoter has identified. Each web site can have a domain name that prominently displays the contact's identity. The psychological benefit to the contact of finding a web site devoted to the contact and with the contact's own identity as part of the domain name conditions the contact favorably and increases the chances that the result sought by the promoter will be achieved." The patent application was filed on May 31, 2011 (13/118,902). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,380,877&OS=8,380,877&RS=8,380,877 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Stratus Technologies Assigned Patent ALEXANDRIA, Va., Feb. 26 -- Stratus Technologies, Hamilton, Bermuda, has been assigned a patent (8,381,012) developed by Garth Dylan Wiebe, Maynard, Mass., for an "apparatus and method for redundant and spread spectrum clocking." The abstract of the patent published by the U.S. Patent and Trademark Office states: "An apparatus and method for fault-tolerant and spread spectrum clocking. In one embodiment a master clock synthesizer circuit generates an output clock signal of varying frequency within a predetermined range of frequencies. A slave clock synthesizer circuit is provided to track the output clock signal generated by the master clock synthesizer circuit. If the master clock synthesizer circuit fails or generates an invalid output clock signal, the slave clock synthesizer circuit takes over and functions as the master clock synthesizer circuit. In one embodiment a method of fault-tolerant spread spectrum clocking includes generating a first digital data stream; receiving the first digital data stream, a first input reference signal and a first clock signal in a master clock synthesizer circuit; generating an first output clock signal of varying frequency by the master clock synthesizer circuit in response to the first digital data stream and the first clock signal." The patent application was filed on March 15, 2012 (13/421,315). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,381,012&OS=8,381,012&RS=8,381,012 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Open Text Assigned Patent for Method and System for Transforming Input Data Streams ALEXANDRIA, Va., Feb. 26 -- Open Text, Luxembourg, has been assigned a patent (8,380,830) developed by Dennis D. Ladd, Acton, Mass., and Anders Hermansson, Gothenburg, Sweden, for a "method and system for transforming input data streams." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A system and method for processing an input data stream in a first data format of a plurality of first data formats to an output data stream in a second data format of a plurality of second data formats. A plurality of input connector modules receive respective input data streams and at least one input queue stores the received input data streams. A plurality of job threads is operatively connected to the at least one input queue, each job thread formatting a stored input data stream to produce an output data stream. At least one output queue stores the output data streams from the plurality of job threads. A plurality of output connector modules is operatively connected to the at least one output queue, the output connector modules supplying respective output data streams." The patent application was filed on April 22, 2011 (13/092,771). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,380,830&OS=8,380,830&RS=8,380,830 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Massachusetts Inventor Develops Patent for Location Based Information System ALEXANDRIA, Va., Feb. 26 -- Robert K. Tendler, Chestnut Hill, Mass., has developed a patent (8,380,224) for a "location based information system." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A wireless device-based system provides location-based services by determining the location of the wireless device and arranges for the service and the payment therefor." The patent application was filed on Sept. 21, 2011 (13/200,292). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,380,224&OS=8,380,224&RS=8,380,224 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Research In Motion Assigned Patent for System and Method for Managing Messages in Conversational-type Messaging Applications ALEXANDRIA, Va., Feb. 26 -- Research In Motion, Waterloo, Canada, has been assigned a patent (8,380,231) developed by Francis Thomas Riddle, Andover, Mass., and John Bennett Parrett, Andover, Mass., for "system and method for managing messages in conversational-type messaging applications." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A system and method are provided for managing messages in conversational-type messaging applications. To provide continuity across all conversations with a particular recipient, an existing or not-yet-created 1:1 conversation can be populated with 1:Many messages that include the same recipient in the list of addressees. In this way, any 1:1 chat or conversation with a particular recipient will contain all correspondences with that recipient, regardless of whether the message was sent or received in a 1:1 or 1:Many context. As such, the user has access to all information that has been exchanged with that recipient in one messaging screen to avoid the need to traverse multiple messaging screens to obtain the context or information related to the recipient that the user requires." The patent application was filed on Feb. 26, 2010 (12/713,314). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,380,231&OS=8,380,231&RS=8,380,231 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Systagenix Wound Management (US) Assigned Patent ALEXANDRIA, Va., Feb. 26 -- Systagenix Wound Management (US), United Kingdom, has been assigned a patent (8,377,651) developed by four co-inventors for a "method for detecting Escherichia coli." The co-inventors are Gerard J. Colpas, Holden, Mass., Diane Ellis-Busby, Lancaster, Mass., Shite Sebastian, Somerville, Mass., and Mitchell C. Sanders, West Boylston, Mass.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Described herein are methods of detecting an infection and for detecting the presence or absence of microorganisms, for example, wound pathogens in a sample, by contacting a sample with an enzyme produced and/or secreted by the bacteria, and detecting modification or the absence of modification of the substrate, as an indicator of the presence or absence of the enzyme in the sample. The present invention also features a biosensor for detecting the presence or absence of bacteria in a sample." The patent application was filed on Sept. 30, 2010 (12/894,212). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,377,651.PN.&OS=PN/8,377,651&RS=PN/8,377,651 Written by Kusum Sangma; edited by Anand Kumar.

*** AstraZeneca Assigned Patent ALEXANDRIA, Va., Feb. 26 -- AstraZeneca, Sodertalje, Sweden, has been assigned a patent (8,377,940) developed by seven co-inventors for an "oxadiazole derivatives and their use as metabotropic glutamate receptor potentiators--842." The co-inventors are Joshua Clayton, Ontario, Canada, Ian Egle, Ontario, Canada, James Empfield, Wilmington, Del., James Folmer, Wilmington, Del., Methvin Isaac, Ontario, Canada, Fupeng Ma, Melrose, Mass., and Abdelmalik Slassi, Ontario, Canada.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Compounds of Formula (I) wherein R.sup.1 and Q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same. ##STR00001##." The patent application was filed on June 5, 2008 (12/663,371). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,377,940.PN.&OS=PN/8,377,940&RS=PN/8,377,940 Written by Kusum Sangma; edited by Anand Kumar.

*** Eisai R&D Management Assigned Patent ALEXANDRIA, Va., Feb. 26 -- Eisai R&D Management, Tokyo, has been assigned a patent (8,377,893) developed by John D. Orr, Amesbury, Mass., for a "highly purified antiendotoxin compound." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The invention provides compositions containing a highly purified antiendotoxin compound and methods of preparing and using such compositions." The patent application was filed on June 16, 2010 (12/816,913). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,377,893.PN.&OS=PN/8,377,893&RS=PN/8,377,893 Written by Kusum Sangma; edited by Anand Kumar.

*** Massachusetts Inventors Develop Patent for Spectrometers with Aberration-corrected Concave Diffraction Gratings and Transmissive Aberration Correctors ALEXANDRIA, Va., Feb. 26 -- Lian-Qin Xiang, Acton, Mass., and Andrew Xiang, Littleton, Mass., have developed a patent (8,379,203) for "spectrometers with aberration-corrected concave diffraction gratings and transmissive aberration correctors." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The invention generally relates to spectrometers and optical systems useful therein. More particularly, the invention generally relates to optical systems and systems having improved functionalities, flexibilities, and design options. For example, optical systems of the invention employ an aberration-corrected concave grating along with one or more transmissive aberration correctors." The patent application was filed on Oct. 19, 2009 (12/809,802). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,79,203.PN.&OS=PN/83,79,203&RS=PN/83,79,203 Written by Kusum Sangma; edited by Anand Kumar.

*** Philips Electronics Assigned Patent for System and Method for Enabling Selection of an Image Registration Transformation ALEXANDRIA, Va., Feb. 26 -- Philips Electronics, Eindhoven, The Netherlands, has been assigned a patent (8,380,007) developed by five co-inventors for a "system and method for enabling selection of an image registration transformation." The co-inventors are Raymond C. Chan, Brookline, Mass., Robert Manzke, Cambridge, Mass., Shunmugavelu Sokka, Brighton, Mass., Volker Rasche, Erbach, Germany, and Vivek Reddy, Boston.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "System and method for enabling intra-operative selection of an image registration transformation for use in displaying a first image dataset and a second image dataset in correspondence with one another. Image dataset acquisition devices (12, 14) obtain the first and second image datasets. A similarity function indicative of a likelihood that the first and second image datasets are in correspondence with one another is computed by a processor (16) and then a ranking of each of a plurality of local maxima of the similarity function is determined. Registration transformations derived from a plurality of the local maxima are displayed on a display (18), and using a user-interface (22), a physician can select each registration transformation to ascertain visually whether it is the clinically-optimal registration transformation for subsequent use." The patent application was filed on Dec. 5, 2006 (12/096,648). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,380,007&OS=8,380,007&RS=8,380,007 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Zalicus Pharmaceuticals Assigned Patent ALEXANDRIA, Va., Feb. 26 -- Zalicus Pharmaceuticals, Vancouver, Canada, has been assigned a patent (8,377,968) developed by nine co-inventors for an "N-piperidinyl acetamide derivatives as calcium channel blockers." The co-inventors are Hassan Pajouhesh, West Vancouver, Canada, Ramesh Kaul, Burnaby, Canada, Yanbing Ding, Richmond, Canada, Yongbao Zhu, Langley, Canada, Lingyun Zhang, Vancouver, Canada, Nagasree Chakka, Cambridge, Mass., Mike Grimwood, North Vancouver, Canada, Jason Tan, Vancouver, Canada, and Yuanxi Zhou, Richmond, Canada.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted T-type calcium channel activity are disclosed. Specifically, a series of compounds containing N-piperidinyl acetamide derivatives as shown in formula (1). ##STR00001##." The patent application was filed on April 8, 2009 (12/420,793). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,377,968.PN.&OS=PN/8,377,968&RS=PN/8,377,968 Written by Kusum Sangma; edited by Anand Kumar.

*** IPSEN Pharma Assigned Patent ALEXANDRIA, Va., Feb. 26 -- IPSEN Pharma, Boulogne, France, has been assigned a patent (8,377,865) developed by Zheng Xin Dong, Holliston, Mass., for a "growth hormone releasing peptides." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Disclosed are peptide and peptidomimetic compounds generally according to formula (I), and pharmaceutically acceptable salts thereof, that are useful as GHRP analogs: R.sup.1-A.sup.1-A.sup.2-A.sup.3-A.sup.4-A.sup.5-R.sup.2 (I) or a pharmaceutically acceptable salt thereof, wherein: A.sup.1 is Aib, Apc or Inp; A.sup.2 is D-Bal, D-Bip, D-Bpa, D-Dip, D-1Nal, D-2Nal, D-Ser(Bzl), or D-Trp; A.sup.3 is D-Bal, D-Bip, D-Bpa, D-Dip, D-1Nal, D-2Nal, D-Ser(Bzl), or D-Trp; A.sup.4 is 2Fua, Orn, 2Pal, 3Pal, 4Pal, Pff, Phe, Pim, Taz, 2Thi, 3Thi, Thr(Bzl); A.sup.5 is Apc, Dab, Dap, Lys, Orn, or deleted; R.sup.1 is hydrogen, (C.sub.1-6)alkyl, (C.sub.5-14)aryl, (C.sub.1-6)alkyl(C.sub.5-14)aryl, (C.sub.3-8)cycloakyl, or (C.sub.2-10)acyl; and R.sup.2 is OH or NH.sub.2; and pharmaceutical compositions and methods of use thereof." The patent application was filed on June 9, 2008 (12/157,224). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,377,865.PN.&OS=PN/8,377,865&RS=PN/8,377,865 Written by Kusum Sangma; edited by Anand Kumar.

*** Novartis Assigned Patent ALEXANDRIA, Va., Feb. 26 -- Novartis, Basel, Switzerland, has been assigned a patent (8,377,978) developed by four co-inventors for a "substituted carbamoylmethylamino acetic acid derivatives as novel NEP inhibitors." The co-inventors are Yuki Iwaki, Cambridge, Mass., Toshio Kawanami, Boston, Gary Michael Ksander, Amherst, Mass., and Muneto Mogi, Waltham, Mass.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention provides a compound of formula I; ##STR00001## or a pharmaceutically acceptable salt thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.6, A.sup.1, A.sup.2, X.sup.1, s and m are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition." The patent application was filed on April 18, 2012 (13/449,357). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,377,978.PN.&OS=PN/8,377,978&RS=PN/8,377,978 Written by Kusum Sangma; edited by Anand Kumar.

*** Canon Assigned Patent ALEXANDRIA, Va., Feb. 26 -- Canon, Tokyo, has been assigned a patent (8,378,997) developed by Tsuyoshi Kuroki, Cambridge, Mass., Christian Sandor, Tokyo, and Shinji Uchiyama, Yokohama, Japan, for an "information processing method and device for presenting haptics received from a virtual object." The abstract of the patent published by the U.S. Patent and Trademark Office states: "At the time of using a haptic device to present to a user haptics which a first virtual object superimposed on the haptic device receives from a second virtual object superimposed on a real object, the user is enabled to touch within the second virtual object, regardless of the real object. Accordingly, the haptics received from the second virtual object is obtained using a first haptic event model of the first virtual object and a second haptic event model of the second virtual object, and while the first haptic event model corresponds to computer graphics information of the first virtual object, the shape of the first virtual object differs from that of the haptic device, such that instructions can be made regarding the inside of the real object, using the first virtual object." The patent application was filed on April 19, 2007 (11/737,695). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,78,997.PN.&OS=PN/83,78,997&RS=PN/83,78,997 Written by Kusum Sangma; edited by Anand Kumar.

*** Massachusetts Inventor Develops Patent for Lensless Imaging with Reduced Aperture ALEXANDRIA, Va., Feb. 26 -- John Farah, Attleboro, Mass., has developed a patent (8,379,214) for a "lensless imaging with reduced aperture." The abstract of the patent published by the U.S. Patent and Trademark Office states: "An image of an object can be synthesized either from the Fourier components of the electric field or from the Fourier components of the intensity distribution. Imaging with a lens is equivalent to assembling the Fourier components of the electric field in the image plane. This invention provides a method and a means for lensless imaging by assembling the Fourier components of the intensity distribution and combining them to form the image with the use of amplitude splitting interferometer. The angular spectrum of the electromagnetic radiation consists of wavefronts propagating at different angles. The amplitude of each wavefront is split and interfered with itself to create sinusoidal fringe patterns having different spatial frequencies. The sinusoidal fringe patterns are combined to form an image of the object. This method applies to coherent and incoherent light." The patent application was filed on March 2, 2009 (12/380,586). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,79,214.PN.&OS=PN/83,79,214&RS=PN/83,79,214 Written by Kusum Sangma; edited by Anand Kumar.

*** AstraZeneca Assigned Patent ALEXANDRIA, Va., Feb. 26 -- AstraZeneca, Sodertalje, Sweden, has been assigned a patent (8,377,939) developed by seven co-inventors for an "oxadiazole derivatives and their use as metabotropic glutamate receptor potentiators 842." The co-inventors are Joshua Clayton, Oakville, Canada, Ian Egle, North York, Canada, James Empfield, Wilmington, Del., James Folmer, Wilmington, Del., Methvin Isaac, Brampton, Canada, Fupeng Ma, Melrose, Mass., and Abdelmalik Slassi, Mississauga, Canada.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Compounds of Formula I: ##STR00001## wherein R.sup.1 and Q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same." The patent application was filed on June 6, 2008 (12/134,553). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,377,939.PN.&OS=PN/8,377,939&RS=PN/8,377,939 Written by Kusum Sangma; edited by Anand Kumar.

*** Nanoscale Labs Assigned Patent ALEXANDRIA, Va., Feb. 26 -- Nanoscale Labs, Rousset, France, has been assigned a patent (8,379,770) developed by Nicolas Sornin, La Tronche, France, and Laurent Perraud, Acton, Mass., for a "signal conversion system for sending or receiving a radiofrequency signal." The abstract of the patent published by the U.S. Patent and Trademark Office states: "System for converting a radiofrequency signal S.sub.RX so as to recover encoded information carried by the signal S.sub.RX, includes generating elements arranged to generate a signal S.sub.LO, mixing elements (3) arranged to generate a signal S.sub.RX-LO by mixing the signal S.sub.RX with the signal S.sub.LO, an analog/digital converter arranged to convert the signal S.sub.RXLO into a digital signal S.sub.RX-LO-Num, a device generating an error correction digital signal S.sub.Cor, the device being arranged so that the signal S.sub.Cor reflects the phase gap between the phase of the signal S.sub.LO and a phase setpoint, the phase setpoint being the phase of an ideal signal S.sub.0, ideal for recovering the encoded information carried by the signal S.sub.RX, combining elements arranged to generate the signal S.sub.0'-Num by combining the signal S.sub.RX-LO-Num with the signal S.sub.Cor. A system for converting a digital signal so as to send a radiofrequency analog signal carrying the information of the digital signal is also described." The patent application was filed on Nov. 21, 2008 (12/744,144). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,379,770&OS=8,379,770&RS=8,379,770 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Basell Poliolefine Italia Assigned Patent ALEXANDRIA, Va., Feb. 26 -- Basell Poliolefine Italia, Milan, Italy, has been assigned a patent (8,378,032) developed by four co-inventors for an "elastoplastic polyolefin compositions having low gloss." The co-inventors are Giampaolo Pellegatti, Boara, Italy, Paolo Goberti, Vigarano Mainarda, Italy, Michael Balow, Brighton, Mich., and Robert Butala, Rosemont, Mass.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Elastoplastic polyolefin composition comprising, in percent by weight: A) 10-50% of a copolymer of propylene with one or more comonomer(s) selected from ethylene and CH.sub.2.dbd.CHR alpha-olefins where R is a 2-8 carbon alkyl, which copolymer contains from 1 to 8% of comonomer(s); B) 50-90% of a copolymer of ethylene and (i) propylene or (ii) CH.sub.2.dbd.CHR alpha-olefins, where R is a 2-8 carbon alkyl radical, or (iii) a combination thereof, optionally with minor amounts of a diene, containing from 57 to 80% of ethylene; wherein the weight ratio B/XS of the content B of copolymer component (B) to the fraction XS soluble in xylene at room temperature, both referred to the total weight of (A)+(B), is of 1.5 or less, and the intrinsic viscosity [.eta.] of the said XS fraction is of 3 dl/g or more." The patent application was filed on March 26, 2012 (13/430,628). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,378,032.PN.&OS=PN/8,378,032&RS=PN/8,378,032 Written by Kusum Sangma; edited by Anand Kumar.

*** Merck Serono Assigned Patent ALEXANDRIA, Va., Feb. 26 -- Merck Serono, Coinsins, Switzerland, has been assigned a patent (8,377,903) developed by four co-inventors for a "cladribine regimen for treating multiple sclerosis." The co-inventors are Giampiero De Luca, Geneva, Switzerland, Arnaud Ythier, Collex-Bossy, Switzerland, Alain Munafo, Tartegnin, Switzerland, and Maria Lopez-Bresnahan, Lincoln, Mass.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention is related to the use of Cladribine for the preparation of a pharmaceutical formulation for the treatment of multiple sclerosis, especially relapsing-remitting multiple sclerosis or early secondary progressive multiple sclerosis, wherein the preparation is to be the orally administered and wherein re-treatments are possible." The patent application was filed on April 23, 2010 (12/766,173). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,377,903.PN.&OS=PN/8,377,903&RS=PN/8,377,903 Written by Kusum Sangma; edited by Anand Kumar.

*** Massachusetts Inventors Develop Patent for Devices and Methods for Converting Wave Energy into Electricity ALEXANDRIA, Va., Feb. 26 -- Gary Steven Sichau, Quincy, Mass., and Zigmunt Michna, New Hartford, Conn., have developed a patent (8,378,511) for "devices and methods for converting wave energy into electricity." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A device that converts kinetic energy of waves of a body of water into electricity comprising a structure responsive to the kinetic energy, a rod extending through the structure; and an electromagnet positioned in the structure, and at least partially surrounding a portion of the rod. The electricity is generated in the rod when the electromagnet rises and falls along the rod in response to the kinetic energy. A magnetic field generated by the electromagnet has a varying strength that is modified according to the amount of kinetic energy to maximize the electricity generated." The patent application was filed on Nov. 18, 2009 (12/592,001). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,78,511.PN.&OS=PN/83,78,511&RS=PN/83,78,511 Written by Kusum Sangma; edited by Anand Kumar.

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